Topic Wise Video Lecture Notes on Biomedical Photonics

Aim of Course
The course should provide knowledge about the physical properties of light and its impact and interaction with biological tissue.
Course Content
Optical properties of biological tissue. Light transport in tissue. Therapeutic window. Light transport models. Measurement of tissue optical properties. Optical coherence tomography, multi-photon excitation, flourescens, etc.

To download all the Video Lecture Notes, Topic wise click on the computer icon on Left hand side.

 

1 I Introduction
Course Content
Why Use Optical Methods?
Why Should You Learn Biomedical Optics?
Fundamentals of Optics
Overview of Spectroscopy
Classical Description of Light
Light-Tissue Interaction
 2 II Basic Optics
What is Light
Short Wavelengths
Radiation Power
Radiation Energy
Radiation Intensity
Collection of Light
Integrating Spheres
Detector
III Tissue Optical Properties
Optical Properties vs Optical Measurements
 3        Absorption
Scattering
Anisotropy
Isotropic Scattering
Anisotropic Values
Summary
 4        Scattering Cases
Rayleight Scattering
Mie Theory Model
Summary Optical Properties
 5 IV Optical Transport in Tissues
Primary Unscattered Light
Demonstration
Optical Fiber in Scattering Medium
Irradiance
1D Model
Fluence Rate
Time-Resolved and Steady-State Fluence Rate
Light Diffusion
Internal Source and Virtual Source
 6 V Transport Equation
The Dualism of Light
Light Propagation in Random Medium
Transport Equation
Monte Carlo Simulations
Radiance L
The Transport Equation
Energy Conservation
The Total Attenuation Coefficient and Albedo
 7 VI Diffusion Equation
Approximations
Spherical Harmonics
Diffusion
Photon Density Function
Photon current Density
Mathematical Simplifications
The Diffusion Coefficient
The Diffusion Equation
Point Source Solution
 8   Light Scattering in Tissue by Monte Carlo Simulation
What is Monte Carlo Modeling?
Program Menu and Steps
End of Monte Carlo Model
 9 VII Optical Properties Measurements
Attenuation of Collimated Beam
Collimated Transmission Calculations
Total Diffuse Reflectance
Optical Penetration Depth
Total Diffuse Reflectance
Calculations
10        Integrating Sphere
Reflection Calculations
Goniometer Principle
Scattering Pattern
CCD Camera with Tilted Source
11 VIII Devices and Protocols
Optical Fiber Bundle
Measurement Situation
Multifiber Probe
Oxygenation and Blood Content
Fluorescence
PDT
12   Polarization
Amplitude Scattering Matrix
Degree of Polarization
Scattering Matrix
System Setup
Polarization Image
Prerequisites
Degree of Polarization
13   QUELS
Evolution
Theory Principle
Anisotropy
Scattering Function
Detection Model
Coherence Area
Photocurrent
16 Terms of E-Fields
Light Beat Detection
The Doppler Component
Wiener –Khintchine Theorem
Perfusion Value
Sampling Volume
LDPM
14   Optical Coherence Tomography
Imaging Methods in Tissue
Optical Coherence Tomography
Temporal Coherence
Coherence Properties
Correlation Functions
Photon Sources
Coherence
Coherence Length
Optical Coherence Tomography
Lightsource Parameters
Optical Coherence Tomography
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