Author Archives: Arthi G

Could Computer Models predict life threatening Heart issues?

Physiologic and Engineering techniques are combined to provide personalized treatments for each patient to predict long-term results. A simpler way to visualize the idea is by imagining that, the doctor pulls up a virtual model of the patient’s heart on the computer and treats it with several drugs and a few moments later, she would be able to see how the heart is doing five years down the road.

The Study

A couple of researchers from The University of Kentucky Kenneth Campbell and Jonathan Wenk are working on building a multiscale simulation of heart by allowing the computer model to use MRI or Genetic data of the patients. They are granted a 3-million-dollar fund by The National Institute of Health.

Inhibiting the protein involved in Phosphorylation may treat Heart disorders

The researchers at Johns Hopkins University School of Medicine are conducting a new study for manufacturing personalized medicine with the help of protein markers for varied level of Phosphorylation.

A form of heart disease known as heart failure with preserved ejection fraction (the amount of blood squeezed out when the heart contracts) impairs the heart’s ability to quickly and efficiently relax between “beats,” overworking the organ. The disease is estimated to impair circulation in more than 23 million people worldwide. Patients with ejection fraction issue preserved at baseline have particular difficulty when they try to increase their activity or exercise unlike the usual issue of shortness of breath that occurs in the other types of heart disorders.

Genetic cause of the Congenital Heart Disease (CHD) discovered!

Congenital Heart disease (CHD) is the defect that occurs in the heart of child right from its birth due to genetic deformity. This could affect any structural part of the Heart such as the walls, valves, arteries, veins etc. CHD being one the most common birth defects has been statistically analyzed to affect 1 in every 100 children. It is also one of the leading causes of mortality from birth defects.

Abnormality in the heart that develops before birth

Can Advanced Heart failure be reversed? Yes, it can be

Heart failure is one of the most dangerous and commonly found diseases in the world affecting more than 26 million people. Heart failure could be alarming because it not only affects the Heart but also most of the other organs too due to the insufficient supply of Oxygen and other vital nutrients. There are several factors such as obesity, high blood pressure, high cholesterol, stress, hereditary causing Heart attack.  On the other side, there are several methods of treatment available through both Transplantation and Implantation. However, there is at least a small amount of discomfort or unreliability prevailing with most techniques [4 &5].