Researchers have discovered the precise chemical chain reaction that could be the much-sought-after puberty trigger: The KiSS-1 gene, which produces a protein in the hypothalamus, a part of the brain, which regulates metabolic activity. When the protein connects with a receptor on another gene called GPR54, puberty is believed to begin. This knowledge may guide the development of better drugs for treating hormone disorders related to puberty.
PITTSBURGH–They’re politely called “the awkward years,” but anybody who can remember going through puberty knows “awkward” is an understatement. Now medical researchers believe they’re close to solving the puzzle of puberty.