Concentrations of Drugs in the Blood are a Balance Between Input and Output
- The concentrations of all chemicals in your body are the result of a balance between input and output.
- For drugs the input is usually a steady injection through an intravenous (IV) line or a periodic uptake through pills taken at regular intervals.
- The output of drugs is mainly through 2 organs, the liver and kidney.
- When the output equals the input a steady-state is attained and the concentration will no longer change:
This is a preview of How the Body Handles Drugs USING Kidney and Liver-INTERESTING FACT. Read the full post (793 words, 5 images, estimated 3:10 mins reading time)
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Basic Kidney Anatomy
- Kidneys paired, about 150 gm each
- Urine forming units:
- Medulla (lobed: renal pyramids)
- Cortex and medulla composed chiefly of nephrons and blood vessels
- Supplied by renal arteries (branches of descending aorta) and renal veins (branches of inferior vena cava)
- Urine collecting and expelling units:
- Renal pelvises
Although the Kidneys are Tiny Organs They Receive 25% of the Cardiac Output