Tag Archives: Robert Langer

Biomedical meets Nanotechnology for Cyborg Tissues

We’re at the cusp of integrating miniaturized electronics and monitoring into engineered tissues and organs.

At the start of the 2009 Star Trek reboot (this is relevant, trust me), the USS Kelvin’s captain meets the enemy on their ship to try to negotiate a cease-fire. His crew uses a kind of sensing technology to track his vital signs—like heart rate, breathing, body temperature—right up to the moment of his untimely demise.

Biomaterials Research: Synthetic Material to replace Vocal Cords

In 1997, the actress and singer Julie Andrews lost her singing voice following surgery to remove noncancerous lesions from her vocal cords. She came to Steven Zeitels, a professor of laryngeal surgery at Harvard Medical School, for help.

Zeitels was already starting to develop a new type of material that could be implanted into scarred vocal cords to restore their normal function. In 2002, he enlisted the help of MIT’s Robert Langer, the David H. Koch Institute Professor in the Department of Chemical Engineering, an expert in developing polymers for biomedical applications.

BIOMEDICAL ENGINEERS ARE GIFTED ONES ALWAYS

There’s Smart, and then there’s Mega-Smart
Biomedical engineers are smart people; this is a universal truth. As a rule, dim-witted people do not develop bioartificial organs or design pacemakers. But then there are the pioneers who have taken the biomedical field by storm over the past century, earning more awards and patents and inventing more devices than any mere mortal should. You could refer to this rare breed as The Ridiculously Smart Bioengineering Club, a league of gifted souls with DNA like Einstein’s.
What Do They Have in Common?
Let’s start with biophysicist Otto Schmitt. Though his parents weren’t scientists, Otto was exposed at the age of 16 to the work of his older brother Frank. Frank became a professor of zoology in 1929, and Otto was allowed to “gadgeteer” in Frank’s laboratory and create instrumentation (www.thebakken.org). Otto would also do experiments at home, much to his mother’s chagrin. His mom fainted when she went into his bedroom one day and saw Otto with sparks flying out of his nose and fingers; he had crafted his own rudimentary Tesla Ball out of spare parts to make his hair stand straight up. Despite his crazy antics with electricity, Otto survived his youth and went on to invent devices like the cathode follower.
Leslie Geddes has taught one-fifth of all biomedical engineers currently in practice. He’s patented everything from a baby pacifier that delivers medication to biomaterials (www.mit.edu). As a kid, Leslie’s dad would bring home radio parts from work for his son to tinker with. Because some relatives were physicians, Leslie decided he would like to combine electronics with medicine.
Extraordinary curiosity is a common theme in the early years of the genius bioengineers. Robert Langer, currently Professor of Chemical Engineering at MIT in Cambridge, received a Gilbert chemistry and microscope set from his parents as a young boy. He was fascinated watching chemical color changes, and enjoyed watching shrimp grow with his little microscope (www.thebiotechclub.org). This young chemist would grow up to receive more than 600 patents and 160 major awards, and be the most cited engineer in history. His controlled drug delivery developments have alleviated human pain for countless patients. The stubborn Langer is oft-quoted as saying, “A lot of times somebody will tell you that your idea, or your invention, can’t be done. I think that’s very rarely true. If you believe in yourself and if you really work hard and stick to it, I believe there is very little that is impossible.”
This stubbornness gene can be found in Alfred E. Mann, entrepreneurial physicist and philanthropist billionaire. He’s said, “To say we can’t do something because other people have failed is not good enough for me” (www.inhealth.org).
It seems the formula for biomedical engineering mega-success is one part insatiable curiosity, one part influence by mentors, two parts giftedness, and three parts stubbornness.
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