Aim of Course
The course should provide knowledge about the physical properties of light and its impact and interaction with biological tissue.
Course Content
Optical properties of biological tissue. Light transport in tissue. Therapeutic window. Light transport models. Measurement of tissue optical properties. Optical coherence tomography, multi-photon excitation, flourescens, etc.
To download all the Video Lecture Notes, Topic wise click on the computer icon on Left hand side.
1 |
I | Introduction Course Content Why Use Optical Methods? Why Should You Learn Biomedical Optics? Fundamentals of Optics Overview of Spectroscopy Classical Description of Light Light-Tissue Interaction |
| 2 |
II | Basic Optics What is Light Short Wavelengths Radiation Power Radiation Energy Radiation Intensity Collection of Light Integrating Spheres Detector |
| III | Tissue Optical Properties Optical Properties vs Optical Measurements |
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| 3 |
Absorption Scattering Anisotropy Isotropic Scattering Anisotropic Values Summary |
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| 4 |
Scattering Cases Rayleight Scattering Mie Theory Model Summary Optical Properties |
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| 5 |
IV | Optical Transport in Tissues Primary Unscattered Light Demonstration Optical Fiber in Scattering Medium Irradiance 1D Model Fluence Rate Time-Resolved and Steady-State Fluence Rate Light Diffusion Internal Source and Virtual Source |
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V | Transport Equation The Dualism of Light Light Propagation in Random Medium Transport Equation Monte Carlo Simulations Radiance L The Transport Equation Energy Conservation The Total Attenuation Coefficient and Albedo |
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VI | Diffusion Equation Approximations Spherical Harmonics Diffusion Photon Density Function Photon current Density Mathematical Simplifications The Diffusion Coefficient The Diffusion Equation Point Source Solution |
| 8 |
Light Scattering in Tissue by Monte Carlo Simulation What is Monte Carlo Modeling? Program Menu and Steps End of Monte Carlo Model |
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| 9 |
VII | Optical Properties Measurements Attenuation of Collimated Beam Collimated Transmission Calculations Total Diffuse Reflectance Optical Penetration Depth Total Diffuse Reflectance Calculations |
| 10 |
Integrating Sphere Reflection Calculations Goniometer Principle Scattering Pattern CCD Camera with Tilted Source |
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| 11 |
VIII | Devices and Protocols Optical Fiber Bundle Measurement Situation Multifiber Probe Oxygenation and Blood Content Fluorescence PDT |
| 12 |
Polarization Amplitude Scattering Matrix Degree of Polarization Scattering Matrix System Setup Polarization Image Prerequisites Degree of Polarization |
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| 13 |
QUELS Evolution Theory Principle Anisotropy Scattering Function Detection Model Coherence Area Photocurrent 16 Terms of E-Fields Light Beat Detection The Doppler Component Wiener –Khintchine Theorem Perfusion Value Sampling Volume LDPM |
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| 14 |
Optical Coherence Tomography Imaging Methods in Tissue Optical Coherence Tomography Temporal Coherence Coherence Properties Correlation Functions Photon Sources Coherence Coherence Length Optical Coherence Tomography Lightsource Parameters Optical Coherence Tomography |
