Tag Archives: Brigham and Women’s Hospital

Tissue Engineering Breakthrough:First Human Lung Stem cell Discovered

Bronchi and bronchioles. The lungs have been w...

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For the first time, researchers at Brigham and Women’s Hospital (BWH) have identified a human lung stem cell that is self-renewing and capable of forming and integrating multiple biological structures of the lung including bronchioles, alveoli and pulmonary vessels. This research is published in the May 12, 2011 issue of the New England Journal of Medicine.

“This research describes, for the first time, a true human lung stem cell. The discovery of this stem cell has the potential to offer those who suffer from chronic lung diseases a totally novel treatment option by regenerating or repairing damaged areas of the lung,” said Piero Anversa, MD, director of the Center for Regenerative Medicine at Brigham and Women’s Hospital and corresponding author.

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GLOBAL VIEW OF BLOOD CELL DEVELOPMENT REVEALS THE PATH OF PROGRESSION

A small pool of stem cells replenishes the human body with about 200 billion new blood cells daily. But the elaborate circuitry that determines if a cell will develop into a T cell, red blood cell, or one of the nine or more other blood cell types remains largely unknown. A research team led by scientists from the Broad Institute and Brigham and Women’s Hospital has taken a systematic approach to help decipher this circuitry, compiling a comprehensive catalog of the factors that determine a blood cell’s fate. Their work appears in the January 21 issue of Cell.

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