Tag Archives: Nanomedicine

Biomechanics of Rat Ovarian cells Charactercized

Researchers characterize biomechanics of ovarian cells in mice according to their phenotype at early, intermediate, and late-aggressive stages of cancer

Using ovarian surface epithelial cells from mice, researchers from Virginia Tech have released findings from a study that they believe will help in cancer risk assessment, cancer diagnosis, and treatment efficiency in a technical journal:Nanomedicine.

By studying the viscoelastic properties of the ovarian cells of mice, they were able to identify differences between early stages of ovarian cancer and more advanced and aggressive phenotypes.

What is Medical Bionics?

Medical Bionics Abstract.jpg

Medical bionics is the replacement or monitoring of damaged organs through engineered devices that interface with the body to improve health outcomes. In this presentation I will concentrate on medical bionic devices designed to restore or supplement function of the nervous system lost during disease or injury.

A number of commercially available neural prostheses will be described – including the remarkably successful bionic ear and deep brain stimulation for movement control.

I will then review some of the current research performed around the world – including recent developments in brain-machine interface that will ultimately allow patients to control prosthetic limbs and wheel chairs; developments in functional electrical stimulation for gait and standing in paraplegia; and research to develop a prosthetic balance system.

Magnetic nanoparticles engineered to capture cancer cells

A paper published in the January issue of the journal Nanomedicine could provide the foundation for a new ovarian cancer treatment option — one that would use an outside-the-body filtration device to remove a large portion of the free-floating cancer cells that often create secondary tumors.

Researchers at the Georgia Institute of Technology have formed a startup company and are working with a medical device firm to design a prototype treatment system that would use magnetic nanoparticles engineered to capture cancer cells. Added to fluids removed from a patient’s abdomen, the magnetic nanoparticles would latch onto the free-floating cancer cells, allowing both the nanoparticles and cancer cells to be removed by magnetic filters before the fluids are returned to the patient’s body.

“BREAST ON CHIP” IN PURDUE UNIVERSITY

Purdue University researchers have reproduced portions of the female breast in a tiny slide-sized model dubbed “breast on-a-chip” that will be used to test nanomedical approaches for the detection and treatment of breast cancer.

The model mimics the branching mammary duct system, where most breast cancers begin, and will serve as an “engineered organ” to study the use of nanoparticles to detect and target tumor cells within the ducts.

Sophie Lelièvre, associate professor of basic medical sciences in the School of Veterinary Medicine, and James Leary, SVM Professor of Nanomedicine and professor of basic medical sciences in the School of Veterinary Medicine and professor of biomedical engineering in the Weldon School of Biomedical Engineering, led the team.