Tag Archives: University of Manchester

PhD IN TISSUE ENGINEERING IN UNIVERSITY OF MANCHESTER

Micro-fabrication of Silk-based Scaffold Materials for Tissue Engineering: Formulation Design, Processing Control and Stem Cell Differentiation
Applications are invited for a Ph.D studentship in School of Chemical Engineering and Analytical Science (http://www.ceas.manchester.ac.uk/), and Manchester Interdisciplinary Biocentre (http://www.mib.ac.uk/), University of Manchester.

Silk produced by the domesticated silkworm, Bombyx mori, is readily available in large quantity and has a long history of use in medicine as sutures. The fibrous proteins exhibit unique mechanical and biological properties, including good biocompatibility, good oxygen and water vapour permeability, biodegradability, and minimal inflammatory reaction. Such distinctive properties, in combination with the possibility of genetic control to tailor sequence, provide an important set of material options for construction of biomaterial and scaffolds for tissue engineering. Recent experimental studies of engineering cartilage tissue using human mesenchymal stem cells (hMST) have demonstrated that silk-based scaffold materials are superior to collagen and synthetic polymer-based scaffold materials.

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PET IMAGING ON ALZHEIMER’S DISEASE TERMED AS LANDMARK BY RESEARCHERS

PET scan of an healthy brain compared to a bra...
Image by Institut Douglas via Flickr

Researchers say a PET imaging agent is able to detect a biomarker for Alzheimer’s disease, in a new study hailed as a “landmark” in the fight against the debilitating disease.

In the study, the amount of beta-amyloid deposits in the brains of the living on a PET scan matched up with what was discovered later during an autopsy.
“It’s a landmark paper, because it’s the first time that, apart from presentations of these data at meetings, …a tracer like that has been validated systematically against neuropathology,” Dr. Karl Herholz, a neurologist with the University of Manchester and president of SNM’s Brain Imaging Council, told DOTmed News. “It’s not a big surprise it’s that good, but it’s certainly important to document that.”

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