Biomedical informatics, as a scientific discipline, has its roots in the early 1970s. It encompasses the fields of bioinformatics, medical imaging, health informatics, and several other disciplines. In recent years, this biological field has experienced explosive growth, due to public access to massive amounts of data generated from the Human Genome Project. A host of other complementary research efforts have also contributed to the knowledge base. This synergistic blend of multiple branches of biology, combined with information technology and knowledge, has enabled researchers and clinicians to utilize an array of information to advance biological research and healthcare.