THE HEART AS A PUMP-CARDIOVASCULAR SYSTEM TUTORIAL

The Right and Left Hearts are Connected in Series, but are Folded Together to Form a Single Unit

  • The right heart pumps blood only to the lungs; its output is low pressure (25 mm Hg)
  • The left heart pumps blood to the rest of the body; its output is high pressure (120 mm Hg)
  • Because the 2 hearts are attached they beat in synchrony
  • The 2 atria receive the incoming blood- they pump extra blood into the ventricles

OXYGEN CARRIED IN BLOOD WHEN PERSON IS AT HIGH ALTITUDE-TUTORIAL PHYSIOLOGY

Oxygen Uptake in the Lungs is Increased About 70X by Hemoglobin in the Red Cells

  • In the lungs oxygen must enter the blood
  • A small amount of oxygen dissolves directly in the serum, but 98.5% of the oxygen is carried by hemoglobin
  • All of the hemoglobin is found within the red blood cells (RBCs or erythrocytes)
  • The hemoglobin content of the blood is about 15 gm/deciliter (deciliter = 100 mL)
  • Red cell count is about 5 million per microliter

Each Hemoglobin Can Bind Four O2 Molecules (100% Saturation)

MECHANISMS IN KIDNEY-TUTORIAL HUMAN PHYSIOLOGY

Section of cortex of human kidney.

Image via Wikipedia

Basic Kidney Anatomy

  • Kidneys paired, about 150 gm each
  • Urine forming units:
    • Cortex
    • Medulla (lobed: renal pyramids)
    • Cortex and medulla composed chiefly of nephrons and blood vessels
    • Supplied by renal arteries (branches of descending aorta) and renal veins (branches of inferior vena cava)
  • Urine collecting and expelling units:
    • Calyces
    • Renal pelvises
    • Ureters
    • Bladder
    • Urethra

Although the Kidneys are Tiny Organs They Receive 25% of the Cardiac Output

WHY SEX? -SEXUAL REPRODUCTION-TECHNICAL POINT OF VIEW FOR DISCUSSION

The sexual cycle
Image via Wikipedia

Sex is Very Costly

  • Large amounts of energy required to find a mate and do the mating: specialized structures and behavior required
  • Intimate contact provides route for infection by parasites (AIDS, syphillis, etc.)
  • Genetic costs: in sex you pass on only half your genes to your children
  • Males are an expensive luxury- in most species they contribute little to rearing offspring

But There are Some Advantages

  • More genetic diversity: more potential for survival of species when environmental conditions change
    • Shuffling of genes in meiosis
    • Crossing-over in meiosis

ELECTRICAL ACTIVITY OF HEART-TUTORIALS

Electrical Activity and EKG

The Cardiac Action Potential Has a Prolonged Refractory Period

  • Heart action potential has a prolonged spike (depolarized)
  • Membrane is refractory for a long time
  • This prevents summation and gives the heart time to fill

All Parts of the Heart Beat Spontaneously

  • Heart muscle does not require stimulation by a nerve
  • Nerves usually inhibit the heart beat; cutting the nerves -> heart speeds up
  • Beat originates as a depolarization in the heart muscle cell itself (self stimulation)
  • All parts of the heart can beat spontaneously

SYNAPSES AND NEUROMUSCULAR JUNCTIONS OF NEURONS-TUTORIAL

Chemical Transmitters Carry the Signal Across Synapses & Neuromuscular Junctions

  • A contact between 2 nerves is called a synapse
  • At the synapse there is a break in electrical transmission (the action potential cannot cross)- instead chemicals are released that carry the signal to the next nerve
    • The release of chemical transmitters at nerve endings was first shown by Otto Loewi in the frog heart
  • A neuromuscular junction (NMJ) is a contact between a nerve and a muscle- it is like a synapse, the action potential stops and the signal is carried by a chemical